2011 Adhesion

• Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells

  Thankamony, S. P. and Sackstein, R.
  Proceedings of the National Academy of Sciences 108
  (8 February 2011); doi: 10.1073/pnas.1018064108

  Abstract

• A Hitchhiker's Guide to Mechanobiology

  Eyckmans, Jeroen, Boudou, Thomas, Yu, Xiang and Chen, Christopher S.
  Developmental Cell 21
  (1 July 2011); doi: 10.1016/j.devcel.2011.06.015

  Abstract

• Blood Vessel Tubulogenesis Requires Rasip1 Regulation of GTPase Signaling

  Xu, Ke et al.
  Developmental Cell 20
  (1 April 2011); doi: 10.1016/j.devcel.2011.02.010

  Abstract

• Analyzing the Anatomy of Integrin Adhesions

  Byron, A.
  Science Signaling 4
  (26 April 2011); doi: 10.1126/scisignal.2001896

  Abstract

• Planar polarized actomyosin contractile flows control epithelial junction remodelling

  Rauzi, Matteo, Lenne, Pierre-François and Lecuit, Thomas
  Nature 468 1110 - 1114
  (10 November 2010); doi: 10.1038/nature09566

  Abstract

• Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration

  Mai, A. et al.
  The Journal of Cell Biology
  (18 July 2011); doi: 10.1083/jcb.201012126

  Abstract

• Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration

  Delorme-walker, V. D. et al.
  The Journal of Cell Biology 193
  (27 June 2011); doi: 10.1083/jcb.201010059

  Abstract

• NMR analysis of the  IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulation

  Metcalf, D. G. et al.
  Proceedings of the National Academy of Sciences 107
  (28 December 2010); doi: 10.1073/pnas.1015545107

  Abstract

• The gap junction protein Cx43 regulates B-lymphocyte spreading and adhesion

  Machtaler, S. et al.
  Journal of Cell Science 124
  (1 August 2011); doi: 10.1242/jcs.089532

  Abstract

• Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption

  Schmidt, S. et al.
  The Journal of Cell Biology 192
  (7 March 2011); doi: 10.1083/jcb.201007141

  Abstract

• Super-Resolution Microscopy: A New Dimension in Focal Adhesions CMC

  Schwartz, Martin Alexander
  Current Biology 21
  (1 February 2011); doi: 10.1016/j.cub.2010.12.025

  Abstract

• In vivo functional analysis reveals specific roles for the integrin-binding sites of talin

  Ellis, S. J., Pines, M., Fairchild, M. J. and Tanentzapf, G.
  Journal of Cell Science 124
  (1 June 2011); doi: 10.1242/jcs.083337

  Abstract

• Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of  1 integrin

  Chen, L. et al.
  Journal of Cell Science 124
  (15 July 2011); doi: 10.1242/jcs.078170

  Abstract

• Interdependency of cell adhesion, force generation and extracellular proteolysis in matrix remodeling

  Kirmse, R., Otto, H. and Ludwig, T.
  Journal of Cell Science 124
  (1 June 2011); doi: 10.1242/jcs.079343

  Abstract

• Adhesion signalling complexes

  Byron, Adam, Morgan, Mark R. and Humphries, Martin J.
  Current Biology 20
  (1 December 2010); doi: 10.1016/j.cub.2010.10.059

  Abstract

• Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration

  Gu, Z., Noss, E. H., Hsu, V. W. and Brenner, M. B.
  The Journal of Cell Biology 193
  (4 April 2011); doi: 10.1083/jcb.201007003

  Abstract

• Loss of Cofilin 1 Disturbs Actin Dynamics, Adhesion between Enveloping and Deep Cell Layers and Cell Movements during Gastrulation in Zebrafish

  Lin, Chun-Wei et al.
  PLoS ONE 5
  (22 December 2010); doi: 10.1371/journal.pone.0015331

  Abstract

• Identification of integrin   subunit mutations that alter affinity for extracellular matrix ligand

  Kendall, T., Mukai, L., Jannuzi, A. L. and Bunch, T. A.
  Journal of Biological Chemistry
  (11 July 2011); doi: 10.1074/jbc.M111.254797

  Abstract

• Cell migration in Drosophila optic lobe neurons is controlled by eyeless/Pax6

  Morante, J., Erclik, T. and Desplan, C.
  Development 138
  (15 February 2011); doi: 10.1242/dev.056069

  Abstract

• Interaction of the Human Prostacyclin Receptor with the PDZ adapter protein PDZK1: Role in Endothelial Cell Migration and Angiogenesis

  Turner, E. C., Mulvaney, E. P., Reid, H. M. and Kinsella, B. T.
  Molecular Biology of the Cell
  (8 June 2011); doi: 10.1091/mbc.E11-04-0374

  Abstract

• Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization

  Slorach, E. M., Chou, J. and Werb, Z.
  Genes & Development 25
  (1 March 2011); doi: 10.1101/gad.1998111

  Abstract

• A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src

  Wang, Y., Cao, H., Chen, J. and Mcniven, M. A.
  Molecular Biology of the Cell 22
  (1 May 2011); doi: 10.1091/mbc.E10-09-0785

  Abstract

• Integrin  5 1 facilitates cancer cell invasion through enhanced contractile forces

  Mierke, C. T. et al.
  Journal of Cell Science 124
  (1 February 2011); doi: 10.1242/jcs.071985

  Abstract

• WAVE Forms Hetero- and Homo-oligomeric Complexes at Integrin Junctions in Drosophila Visualized by Bimolecular Fluorescence Complementation

  Gohl, C., Banovic, D., Grevelhorster, A. and Bogdan, S.
  Journal of Biological Chemistry 285
  (17 December 2010); doi: 10.1074/jbc.M110.139337

  Abstract

• Actomyosin-generated tension controls the molecular kinetics of focal adhesions CMC

  Wolfenson, H., Bershadsky, A., Henis, Y. I. and Geiger, B.
  Journal of Cell Science 124
  (1 May 2011); doi: 10.1242/jcs.077388

  Abstract

• Rab13-dependent Trafficking of RhoA Is Required for Directional Migration and Angiogenesis

  Wu, C. et al.
  Journal of Biological Chemistry 286
  (1 July 2011); doi: 10.1074/jbc.M111.245209

  Abstract

• Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

  Schiller, Herbert B, Friedel, Caroline C, Boulegue, Cyril and Fässler, Reinhard
  EMBO reports 12 259 - 266
  (11 February 2011); doi: 10.1038/embor.2011.5

  Abstract

• Association between  4 integrin cytoplasmic tail and non-muscle myosin IIA regulates cell migration

  Rosado, L. A. R. et al.
  Journal of Cell Science 124
  (1 February 2011); doi: 10.1242/jcs.074211

  Abstract

• Integrins and cadherins join forces to form adhesive networks

  Weber, G. F., Bjerke, M. A. and Desimone, D. W.
  Journal of Cell Science 124
  (15 April 2011); doi: 10.1242/jcs.064618

  Abstract

• Maspin, the Molecular Bridge between the Plasminogen Activator System and  1 Integrin That Facilitates Cell Adhesion

  Endsley, M. P. et al.
  Journal of Biological Chemistry 286
  (15 July 2011); doi: 10.1074/jbc.M111.235788

  Abstract

• Structural Requirements for Activation in  IIb 3 Integrin

  Kamata, T. et al.
  Journal of Biological Chemistry 285
  (3 December 2010); doi: 10.1074/jbc.M110.139667

  Abstract

• Calpain-mediated Proteolysis of Paxillin Negatively Regulates Focal Adhesion Dynamics and Cell Migration

  Cortesio, C. L. et al.
  Journal of Biological Chemistry 286
  (25 March 2011); doi: 10.1074/jbc.M110.187294

  Abstract

• Cdc42-dependent formation of the ZO-1/MRCKβ complex at the leading edge controls cell migration

  Huo, Lin et al.
  The EMBO Journal 30 665 - 678
  (14 January 2011); doi: 10.1038/emboj.2010.353

  Abstract

• Mesenchymal stem cell migration is regulated by fibronectin through  5 1-integrin-mediated activation of PDGFR-  and potentiation of growth factor signals

  Veevers-lowe, J., Ball, S. G., Shuttleworth, A. and Kielty, C. M.
  Journal of Cell Science 124
  (15 April 2011); doi: 10.1242/jcs.076935

  Abstract

• Phosphorylation of Trask by Src Kinases Inhibits Integrin Clustering and Functions in Exclusion with Focal Adhesion Signaling

  Spassov, D. S. et al.
  Molecular and Cellular Biology 31
  (15 February 2011); doi: 10.1128/MCB.00841-10

  Abstract

• The CD157-Integrin Partnership Controls Transendothelial Migration and Adhesion of Human Monocytes

  Lo buono, N. et al.
  Journal of Biological Chemistry 286
  (27 May 2011); doi: 10.1074/jbc.M111.227876

  Abstract

• Mechanisms of mechanical signaling in development and disease

  Janmey, P. A. and Miller, R. T.
  Journal of Cell Science 124
  (1 January 2011); doi: 10.1242/jcs.071001

  Abstract

• Migrational Guidance of Neutrophils Is Mechanotransduced via High-Affinity LFA-1 and Calcium Flux

  Dixit, N., Yamayoshi, I., Nazarian, A. and Simon, S. I.
  The Journal of Immunology 187
  (1 July 2011); doi: 10.4049/jimmunol.1004197

  Abstract

• Adhesion shapes T cells for prompt and sustained T-cell receptor signalling

  Contento, Rita Lucia et al.
  The EMBO Journal 29 4035 - 4047
  (15 October 2010); doi: 10.1038/emboj.2010.258

  Abstract

• Dermatopontin Interacts with Fibronectin, Promotes Fibronectin Fibril Formation, and Enhances Cell Adhesion

  Kato, A. et al.
  Journal of Biological Chemistry 286
  (29 April 2011); doi: 10.1074/jbc.M110.179762

  Abstract

• Cell-ECM traction force modulates endogenous tension at cell-cell contacts

  Maruthamuthu, V., Sabass, B., Schwarz, U. S. and Gardel, M. L.
  Proceedings of the National Academy of Sciences 108
  (22 March 2011); doi: 10.1073/pnas.1011123108

  Abstract

• Shroom2 regulates contractility to control endothelial morphogenesis

  Farber, M. J., Rizaldy, R. and Hildebrand, J. D.
  Molecular Biology of the Cell 22
  (15 March 2011); doi: 10.1091/mbc.E10-06-0505

  Abstract

• The Rho Target PRK2 Regulates Apical Junction Formation in Human Bronchial Epithelial Cells

  Wallace, S. W., Magalhaes, A. and Hall, A.
  Molecular and Cellular Biology 31
  (1 January 2011); doi: 10.1128/MCB.01001-10

  Abstract

• Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

  Lynch, C. D. et al.
  Molecular Biology of the Cell 22
  (15 April 2011); doi: 10.1091/mbc.E10-08-0661

  Abstract

• High-Resolution Quantification of Focal Adhesion Spatiotemporal Dynamics in Living Cells

  Berginski, Mathew E. et al.
  PLoS ONE 6
  (14 July 2011); doi: 10.1371/journal.pone.0022025

  Abstract

• FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion

  Deramaudt, T. B. et al.
  Molecular Biology of the Cell 22
  (1 April 2011); doi: 10.1091/mbc.E10-08-0725

  Abstract

• An Adhesion-Dependent Switch between Mechanisms That Determine Motile Cell Shape CMC

  Barnhart, Erin L. et al.
  PLoS Biology 9
  (3 May 2011); doi: 10.1371/journal.pbio.1001059

  Abstract

• Spatiotemporal Constraints on the Force-Dependent Growth of Focal Adhesions

  Stricker, Jonathan, Aratyn-schaus, Yvonne, Oakes, Patrick W. and Gardel, Margaret L.
  Biophysical Journal 100
  (1 June 2011); doi: 10.1016/j.bpj.2011.05.023

  Abstract

• Structure-Function Analysis of Tetraspanin CD151 Reveals Distinct Requirements for Tumor Cell Behaviors Mediated by  3 1 versus  6 4 Integrin

  Zevian, S., Winterwood, N. E. and Stipp, C. S.
  Journal of Biological Chemistry 286
  (4 March 2011); doi: 10.1074/jbc.M110.173583

  Abstract

• A p27kip1-binding Protein, p27RF-Rho, Promotes Cancer Metastasis via Activation of RhoA and RhoC

  Hoshino, D., Koshikawa, N. and Seiki, M.
  Journal of Biological Chemistry 286
  (28 January 2011); doi: 10.1074/jbc.M110.159715

  Abstract

• Keratinocyte-derived Laminin-332 Promotes Adhesion and Migration in Melanocytes and Melanoma

  Chung, H., Suh, E.-K., Han, I.-O. and Oh, E.-S.
  Journal of Biological Chemistry 286
  (15 April 2011); doi: 10.1074/jbc.M110.166751

  Abstract

• Low Cholesterol Triggers Membrane Microdomain-dependent CD44 Shedding and Suppresses Tumor Cell Migration

  Murai, T. et al.
  Journal of Biological Chemistry 286
  (21 January 2011); doi: 10.1074/jbc.M110.184010

  Abstract

• Interplay of RhoA and Motility in the Programmed Spreading of Daughter Cells Postmitosis

  Mali, Prashant, Wirtz, Denis and Searson, Peter C.
  Biophysical Journal 99
  (1 December 2010); doi: 10.1016/j.bpj.2010.10.006

  Abstract

• Dynamic molecular processes mediate cellular mechanotransduction

  Hoffman, Brenton D., Grashoff, Carsten and Schwartz, Martin A.
  Nature 475 316 - 323
  (20 July 2011); doi: 10.1038/nature10316

  Abstract

• Vascular Endothelial Growth Factor A (VEGF-A) Induces Endothelial and Cancer Cell Migration through Direct Binding to Integrin  9 1: IDENTIFICATION OF A SPECIFIC  9 1 BINDING SITE

  Oommen, S., Gupta, S. K. and Vlahakis, N. E.
  Journal of Biological Chemistry 286
  (14 January 2011); doi: 10.1074/jbc.M110.175158

  Abstract

• Real-Time Monitoring of Epithelial Cell-Cell and Cell-Substrate Interactions by Infrared Surface Plasmon Spectroscopy

  Yashunsky, Victor et al.
  Biophysical Journal 99
  (15 December 2010); doi: 10.1016/j.bpj.2010.10.017

  Abstract

• Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

  Hiratsuka, S. et al.
  Proceedings of the National Academy of Sciences 108
  (1 March 2011); doi: 10.1073/pnas.1100446108

  Abstract

• Endothelial Cell-Specific Molecule 2 (ECSM2) Localizes to Cell-Cell Junctions and Modulates bFGF-Directed Cell Migration via the ERK-FAK Pathway

  Shi, Chunwei et al.
  PLoS ONE 6
  (24 June 2011); doi: 10.1371/journal.pone.0021482

  Abstract

• The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo

  Woodfin, Abigail et al.
  Nature Immunology 12 761 - 769
  (26 June 2011); doi: 10.1038/ni.2062

  Abstract

• Vinculin Activation Is Necessary for Complete Talin Binding

  Golji, Javad, Lam, Johnny and Mofrad, Mohammad R.K.
  Biophysical Journal 100
  (19 January 2011); doi: 10.1016/j.bpj.2010.11.024

  Abstract

• The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

  Guilluy, Christophe et al.
  Nature Cell Biology 13 722 - 727
  (15 May 2011); doi: 10.1038/ncb2254

  Abstract

• Cancer Cells Cut Homophilic Cell Adhesion Molecules and Run

  Craig, S. E. L. and Brady-kalnay, S. M.
  Cancer Research 71
  (15 January 2011); doi: 10.1158/0008-5472.CAN-10-2301

  Abstract

• Specific Syndecan-1 Domains Regulate Mesenchymal Tumor Cell Adhesion, Motility and Migration

  Zong, Fang et al.
  PLoS ONE 6
  (23 June 2011); doi: 10.1371/journal.pone.0014816

  Abstract

• Endocytosis Regulates Cell Soma Translocation and the Distribution of Adhesion Proteins in Migrating Neurons

  Shieh, Jennifer C. et al.
  PLoS ONE 6
  (22 March 2011); doi: 10.1371/journal.pone.0017802

  Abstract

• The insider's guide to leukocyte integrin signalling and function

  Hogg, Nancy, Patzak, Irene and Willenbrock, Frances
  Nature Reviews Immunology 11 416 - 426
  (20 May 2011); doi: 10.1038/nri2986

  Abstract

• Identification of Endothelial Cell Junctional Proteins and Lymphocyte Receptors Involved in Transendothelial Migration of Human Effector Memory CD4+ T Cells

  Manes, T. D. and Pober, J. S.
  The Journal of Immunology 186
  (1 February 2011); doi: 10.4049/jimmunol.1002835

  Abstract

• Forkhead Transcription Factor Foxq1 Promotes Epithelial-Mesenchymal Transition and Breast Cancer Metastasis

  Zhang, H. et al.
  Cancer Research 71
  (15 February 2011); doi: 10.1158/0008-5472.CAN-10-2825

  Abstract

• Ligand-independent activation of c-Met by fibronectin and α₅β₁-integrin regulates ovarian cancer invasion and metastasis

  Mitra, A K et al.
  Oncogene 30 1566 - 1576
  (29 November 2010); doi: 10.1038/onc.2010.532

  Abstract

• The Effect of a DNA Repair Gene on Cellular Invasiveness: Xrcc3 Over-Expression in Breast Cancer Cells

  Martinez-marignac, Veronica L. et al.
  PLoS ONE 6
  (24 January 2011); doi: 10.1371/journal.pone.0016394

  Abstract

• Full-Length L1CAM and Not Its Δ2Δ27 Splice Variant Promotes Metastasis through Induction of Gelatinase Expression

  Hauser, Stephanie et al.
  PLoS ONE 6
  (25 April 2011); doi: 10.1371/journal.pone.0018989

  Abstract

• Regulated Expression of ADAMTS-12 in Human Trophoblastic Cells: A Role for ADAMTS-12 in Epithelial Cell Invasion?

  Beristain, Alexander G., Zhu, Hua, Leung, Peter C. K. and Hotchin, Neil A.
  PLoS ONE 6
  (11 April 2011); doi: 10.1371/journal.pone.0018473

  Abstract

• An In Vitro Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer

  Katz, Elad et al.
  PLoS ONE 6
  (15 February 2011); doi: 10.1371/journal.pone.0017083

  Abstract